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    primidone
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    Melatonin And Stress

    Melatonin has been shown to have a stabilizing influence on the electrical activity of the brain (Brailowsky, 1976). It reduced sensory induced epilepsy and made the EEG to become more synchronized (Miles and Philfrick, 1988). Melatonin improved the efficiency and architecture of sleep. After awakening, the subjects who had used melatonin felt refreshed, had no hangover associated with many sleeping pills and felt well and energetic for the rest of the day. Melatonin appears to be a natural sedative against stress (Waldhausser, et al., 1984). In cases of stress produced by jet lag, melatonin was able to abolish the symptoms of stress and anxiety.

    Yogis have incorporated "Amaroli" as an aid to meditation (Mukibodhanandra, 1983). This is a method of obtaining melatonin by drinking first morning urine which contains melatonin (Bartsch and Bartsch, 1981).

    In one hundred patients taking melatonin, the only consistent effect observed was mild sedation and analgesia (Lerner, et al., 1978; Wetterberg, 1977). Volrath, et al., (1975), demonstrated that melatonin nasal spray produced sleep and a subsequent feeling of emotional balance in 7 of the 10 patients as compared to 1 in 10 in the placebo group.

    Anton-Tay found that after melatonin administration to ten subjects the subjects experienced slowing of EEG, increased visual imagery and a subjective feeling of elation. Thus, melatonin promotes tranquillity and enhances meditation effects (Romijn, et al., 1975).



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