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    Diabetes is a very serious disease. As a matter of fact, many gerontologists consider diabetes as a model of aging. There are two types of diabetes. Type 1 occurs in younger people (it accounts for 10% of diabetes) and is characterized by lack of insulin. These patients need insulin injections for their treatment. Type 2 diabetes (the most common type) occurs in older patients in whom there is a decrease of insulin release from the pancreas which is normally stimulated by glucose in the blood. Since insulin's function is to bring glucose from the blood into the cells, the inadequate amount of insulin released results in higher levels of glucose in the blood. The consequences of this type of diabetes lead to changes in the whole body, leading to further damages to circulation, blindness, cataracts, strokes, kidney and liver damage, neuropathy and infections,sleep problems and high cholesterol.

    In 1986, O'Brien, et al., compared nocturnal melatonin of diabetic patients with age-matched controls. They found that diabetic patients had lower nocturnal melatonin levels than the control group. In addition, patients with diabetes and autonomic neuropathy produced more melatonin during the day than at night.

    During sleep we produce growth hormone which raises blood sugar. Melatonin helps to regulate growth hormone and thus may keep blood glucose lower. Stress increases production of corticosteroids which in turn increase production of glucose.

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