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A recent study suggests that the Helicobacter pylori bacterium may be involved in some cases of iron deficiency anemia, and that treating the H.pylori could improve the anemia as well.
Researchers from University La Sapienza in Rome, Italy, studied a group of 24 patients with iron deficiency anemia who were also infected with H.pylori. They had no gastrointestinal bleeding or any other cause of the anemia.
This is important, because scientists have known that it is not uncommon for individuals with ulcers to also be anemic as a result of bleeding from the ulcer. Scientists also know that H.pylori is involved in many ulcers and cases of gastric cancer. Researchers recently observed that in children and one adult with H.pylori infection, their iron deficiency anemia resolved after the H.pylori was eradicated.
What researchers don't know is whether the anemia resolved because a source of blood loss (an ulcer) was treated, or because the H.pylori somehow was interfering with iron absorption, which then normalized after H.pylori treatment.
That's why these researchers were careful to include only patients with H.pylori infection and iron deficiency anemia in the study, so that the anemia could not be explained by any other condition. The participants were all treated for H.pylori and monitored at intervals for one year. They received no treatment for the anemia, and at six months 75 percent of the participants whose H.pylori had been eradicated experienced a reversal of their anemia. After 12 months 91.7 percent of the participants had recovered from the anemia without additional treatment.
These researchers still don't know the exact way that H.pylori causes iron deficiency anemia in some people, and they caution that larger studies are needed; however, they believe that their study establishes a clear link between the H.pylori bacterium and iron deficiency anemia.