bethanechol

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    bethanechol
    urecholine

    it is also best known as urecholine

    products containing  bethanechol:
    duvoid, mechotane, mechothane, mecothane, mictone, mictrol, myocholine, myotonachol, myotonine chloride, urabeth, urecholine chloride, uro-carb

    amidopropyldimethylbetaine, beta-methyl carbachol chloride, besacholine, bethaine choline chloride, bethanechol chloride, carbamylmethylcholine chloride

    it is also known as:
    trade name generic name
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    Tumors

    Kidney-sparing surgery for kidney cancer, in which only part of the organ is removed, is necessary when a patient has problems with the other kidney. The procedure has become more common in patients whose cancer is localized and at an early stage. A recent study confirms that this procedure allows some cancer patients to live many years with normal kidney function and without recurrence of their cancer.

    Researchers at the Cleveland Clinic Foundation in Cleveland, Ohio, followed 107 kidney cancer patients who had partial nephrectomy--surgery that removed only part of the affected kidney. All of the patients received surgery before 1988, and were followed for at least 10 years or until they died. The 34 women and 73 men had an average age of 60.

    Most of the patients had kidney-sparing surgery because their other kidney was impaired or because their cancer affected both kidneys. About two-thirds had symptoms of cancer; the remaining cancers were identified before symptoms appeared.

    At the end of the study, all of the patients with smaller tumors in only one kidney were alive, and none had a recurrence of their cancer. Patients with cancer in both kidneys were three to five times more likely to die of kidney cancer than those with tumors on just one, and patients with more advanced tumors were four to eight times more likely to die of the cancer than those with cancer in early stages.

    For each 1 cm increase in tumor size over 4 cm, the risk of dying from kidney cancer increased by 20 percent. For example, a patient whose tumor measured 9 cm was twice as likely to die as one whose tumor was less than 4 cm in diameter.

    Even though most of these patients were actually considered high-risk, only 27 percent of patients died of kidney cancer within 10 years, and all had larger and more advanced tumors. In addition, 100 of the 107 patients were able to avoid kidney failure, and even the seven whose kidneys eventually did fail averaged almost 10 years before they needed dialysis.

    Writing in the February 2000 issue of the Journal of Urology, the researchers conclude that this kind of surgery is effective in the long term for kidney cancer patients. They recommend long-term follow-up to detect delayed recurrence, as well as for patients with pre-existing kidney problems.



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